GENERAL CATALOGUE
Cucurbitacin IIb
HY-N1987 · 5 mg
MedChemExpress · Cat: HY-N1987
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Catalog No: HY-N1987
CAS No: 50298-90-3
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of I?B and NF-?B p65 , blocks nuclear translocation of NF-?B p65 and decreases mRNA levels of I?B? and TNF-?.
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