

HY-168085 · 50 mg
MedChemExpress · Cat: HY-168085
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Manufacturer product page
medchemexpress.com/cv-4-26.html
Description
CV-4-26 Compound 22 is a covalent inhibitor of TEAD. CV-4-26 inhibits YAP/TEAD-based transcription, leading to the reduction of CTGF and CYR61 expression. CV-4-26 inhibits Huh7 and HepG2 cell colony formation, induces cell cycle arrest, and apoptosis. CV-4-26 shows antitumor activity against hepatocellular carcinoma HCC and hepatoblastoma HB .







