GENERAL CATALOGUE
CW-2
HY-173437 · 50 mg
MedChemExpress · Cat: HY-173437
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/cw-2.html
Sponsored
Catalog No: HY-173437
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
CW-2 is a PARP1 PROTAC degrader. CW-2 has potent antiproliferative effects against MDA-MB-231 cells IC50 = 0.72 ?M and CDDP-resistant cells A549/CDDP: IC50 = 3.52 ?M . CW-2 has synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts antitumor effects by inducing DNA damage, impairing DNA repair, and activating mitochondria-dependent apoptosis Pink: PARP1 ligand HY-173441 ; Blue: E3 CRBN ligand HY-173439 ; Black: linker HY-173440 .
More from MedChemExpress
TP-061
HY-103041
Cell Cycle DNA Damage
Guttiferone G
HY-N9892
Cell Cycle DNA Damage
C
Cdk14 Mouse Pre-designed siRNA Set A
HY-RS02363
Cell Cycle DNA Damage
HSP70/SIRT2-IN-2
HY-149638
Cell Cycle DNA Damage
Tucidinostat (Standard)
HY-109015R
Cell Cycle DNA Damage
C
CDK2 Human Pre-designed siRNA Set A
HY-RS02374
Cell Cycle DNA Damage
Palmitic acid-d2-1
HY-N0830S11
Cell Cycle DNA Damage
Cdc7-IN-1
HY-101523
Cell Cycle DNA Damage