GENERAL CATALOGUE
CXCR4 antagonist 5
HY-146372 · 50 mg
MedChemExpress · Cat: HY-146372
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/cxcr4-antagonist-5.htmlCatalog No: HY-146372
CAS No: 2304749-86-6
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
CXCR4 antagonist 5 compound 23 is a highly potent CXCR4 antagonist with an IC50 value of 8.8 nM. CXCR4 antagonist 5 can inhibit CXCL12-induced cytosolic calcium increase IC50 = 0.02 nM and inhibits CXCR4/CXLC12-mediated chemotaxis. CXCR4 antagonist 5 has good physicochemical properties and in vitro safety profiles, inhibiting CYP isozymes and hERG marginally or moderately.