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Cyano-myracrylamide
GENERAL CATALOGUE

Cyano-myracrylamide

HY-155938 · 1 mg

MedChemExpress · Cat: HY-155938

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Catalog No: HY-155938
CAS No: 2801702-34-9
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress

Description

Cyano-myracrylamide is an inhibitor of zinc finger DHHC domain-containing palmitoyltransferase 20 zDHHC20 with an IC50 value of 1.35 AAasAasAAmuM. Cyano-myracrylamide also inhibits the S-Acylation of EGFR and CD36. Cyano-myracrylamide also inhibits S-acylation of Legionella E3 ligase GobX, MyD88, and Ras, which are substrates of zDHHC20, zDHHC9, and zDHHC6, respectively, in HEK293T cells expressing recombinant Legionella GobX, recombinant human MyD88, or endogenous Ras.

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