Cyclic GMP (TBAOH)

Description

Cyclic GMP cGMP TBAOH, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide NO and natriuretic peptides NPs . Effects of Cyclic GMP TBAOH occur through three main groups of cellular targets: cGMP-dependent protein kinases PKGs , cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP Cyclic-GMP-AMP HY-12512 , a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses.