GENERAL CATALOGUE
CYP3A4-IN-4
HY-169217 · 50 mg
MedChemExpress · Cat: HY-169217
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Catalog No: HY-169217
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
CYP3A4-IN-4 compound ?,?-3 , a Ru II ?Ir III Conjugate, is a photoactive inhibitor of the major human drug metabolizing enzyme CYP3A4. CYP3A4-IN-4 containing the Ru tpy Me2bpy photocaging group showed an IC50 of 2.2 ?M for inhibition of microsomal CYP3A4 under light conditions ?irr=530 nm, tirr=15 min . CYP3A4-IN-4 shows the phototherapeutic index PI for of 5.4.
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