GENERAL CATALOGUE
CYP3cide
HY-18642 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-18642
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Catalog No: HY-18642
CAS No: 1390637-82-7
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
CYP3cide PF-4981517 is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 CYP3A4 . The IC50 values for Midazolam 1AAasAasAa-hydroxylase activity are 0.03 ?M, 17 ?M, and 71 ?M for CYP3A4, CYP3A5, and CYP3A7, respectively. CYP3cide can be used to distinguish the contributions of CYP3A4 versus CYP3A5 on agent metabolism.
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