GENERAL CATALOGUE
Cytochalasin D
HY-N6682 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N6682
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Catalog No: HY-N6682
CAS No: 22144-77-0
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Cytochalasin D Zygosporin A is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actinAAasAasAacofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap.
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