GENERAL CATALOGUE
CZC-54252 hydrochloride
HY-B0792A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-B0792A
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medchemexpress.com/czc-54252-hydrochloride.html
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Catalog No: HY-B0792A
CAS No: 1784253-05-9
Category: Autophagy
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
CZC-54252 hydrochloride is a potent and selective LRRK2 inhibitor with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2, respectively. G2019S LRRK2-induced human neuronal injury is attenuated by CZC-54252 hydrochloride with an EC50 of 1 nM.CZC-54252 hydrochloride has a neuroprotective activity.
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