GENERAL CATALOGUE
D18
HY-144501 · 1 mg
MedChemExpress · Cat: HY-144501
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Catalog No: HY-144501
CAS No: 2230218-36-5
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
D18 is an immune modulator. D18 acts as a TLR7/8 dual agonist EC50 = 24 nM for hTLR7 and 10 nM for hTLR8, respectively . D18 increases PD-L1 expression through epigenetic regulation, thus sensitizing tumors to PD-1/PD-L1 blockade. D18 is a ADC cytotoxin uesd for the systhesis of ADC HE-S2 HY-144497 . D18 has strong immune activation and anti-tumor activity. D18 commonly used in cancer research, such as colon cancer.
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