

HY-156374 · 5 mg
MedChemExpress · Cat: HY-156374
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Manufacturer product page
medchemexpress.com/d359-0396.html
Description
D359-0396 is an orally active NLRP3 inflammasome inhibitor. D359-0396 inhibits pyroptosis and IL-1? release in macrophages. D359-0396 also inhibits the oligomerization of NLRP3, ASC and the cleavage of GSDMD. D359-0396 alleviates EAE, and also improves survival after septic shock in mice.







