GENERAL CATALOGUE
Dac590
HY-174979 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-174979
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Catalog No: HY-174979
CAS No: 3084407-00-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Dac590 is an orally active FTO inhibitor. Dac590 has a robust antiproliferative effect on AML cells, and induces apoptosis and cell cycle G1 arrest by inhibiting oncogenic FTO signaling. Dac590 significantly inhibits tumor growth and prolongs survival with no observed toxicity in acute myeloid leukemia AML xenograft mcie model, and shows a synergistic effect combined with Decitabine HY-A0004 .
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