GENERAL CATALOGUE
Dalotuzumab
HY-P99284 · 1 mg
MedChemExpress · Cat: HY-P99284
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medchemexpress.com/dalotuzumab.html
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Catalog No: HY-P99284
CAS No: 1005389-60-5
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Dalotuzumab MK-0646 is a recombinant humanized monoclonal antibody IgG1 type targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.
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