GENERAL CATALOGUE
Danicopan
HY-117930 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-117930
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Catalog No: HY-117930
CAS No: 1903768-17-1
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Danicopan ACH-4471 , a selective and orally active small-molecule factor D inhibitor, shows high binding affinity to human Factor D with Kd value of 0.54 nM. Danicopan ACH-4471 inhibits alternative pathway of complement APC activity, has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria PNH and atypical hemolytic uremic syndrome aHUS .
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