GENERAL CATALOGUE
Danoprevir
HY-10238 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10238
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Manufacturer product page
medchemexpress.com/Danoprevir.htmlCatalog No: HY-10238
CAS No: 850876-88-9
Category: Anti-infection
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Danoprevir ITMN-191 is an orally active NS3/4A protease inhibitor for hepatitis C virus HCV with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases IC50 higher than 10 ?M . Danoprevir ITMN-191 inhibits HCV genotypes 1a, 1b, 4, 5, and 6 IC50s=0.2-0.4 nM as well as 2b and 3a IC50s=1.6, 3.5 nM . Danoprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 0.05 ?M.
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