

HY-10181A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10181A
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medchemexpress.com/Dasatinib-hydrochloride.htmlDescription
Dasatinib BMS-354825 hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively. Dasatinib hydrochloride also induces apoptosis and autophagy.







