GENERAL CATALOGUE
dASK1
HY-174862 · 50 mg
MedChemExpress · Cat: HY-174862
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Catalog No: HY-174862
CAS No: 3064086-31-0
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
dASK1 is a selective and cereblon CRBN -based PROTAC degrader of apoptosis signal-regulating kinase 1 ASK1 . dASK1 forms a stable ternary complex with ASK1, facilitating ASK1 rapid and sustained degradation via the ubiquitin-proteasome pathway. dASK1 demonstrates potent ASK1 degradation. dASK1 can be used for the research of steatohepatitis. Structure Note: Pink: ASK1 ligand HY-174860 ; Blue: CRBN ligand HY-10984 ; Black: linker; E3-linker HY-174863
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