GENERAL CATALOGUE
Dasminapant
HY-125593 · 1 mg
MedChemExpress · Cat: HY-125593
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Catalog No: HY-125593
CAS No: 1570231-89-8
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Dasminapant APG-1387 , a bivalent SMAC mimetic and an IAP antagonist, blocks the activity of IAPs family proteins XIAP, cIAP-1, cIAP-2, and ML-IAP . Dasminapant induces degradation of cIAP-1 and XIAP proteins, as well as caspase-3 activation and PARP cleavage, which leads to apoptosis. Dasminapant can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma.
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