GENERAL CATALOGUE
dAurAB2
HY-171769 · 5 mg
MedChemExpress · Cat: HY-171769
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medchemexpress.com/daurab2.html
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Catalog No: HY-171769
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
dAurAB2 is a dual-degrading PROTAC that potently degrades Aurora-A and Aurora-B with DC50s of 59?nM and 39?nM, respectively. dAurAB2 reduces N-Myc levels in MYCN-amplified IMR32 neuroblastoma cells. dAurAB2 can be used for the study of neuroblastoma. Pink, Aurora ligand HY-10804 ; Blue, E3 ligand: HY-103597 ; Black, linker HY-W105740 .
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