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dAurAB5
GENERAL CATALOGUE

dAurAB5

HY-171770 · 1 mg

MedChemExpress · Cat: HY-171770

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Manufacturer product page

medchemexpress.com/daurab5.html
Catalog No: HY-171770
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress

Description

dAurAB5 is a dual Aurora-A DC50 = 8.8 nM and Aurora-B DC50 = 6.1 nM PROTAC degrader. dAurAB5 induces degradation of Aurora-A and Aurora-B, reduces N-Myc levels, and decreases viability in IMR32 neuroblastoma cells. dAurAB5 downregulates the levels of AAK1, PTK2, GAK, and TTK. dAurAB5 can be used to study cancers such as neuroblastoma. Pink: TTK ligand 2: HY-168542, Blue: Thalidomide-O-COOH: HY-103597, Black: 6-Aminocaproic acid: HY-B0236 .

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