GENERAL CATALOGUE
DB1976
HY-135797 · 50 mg
MedChemExpress · Cat: HY-135797
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Catalog No: HY-135797
CAS No: 1557397-51-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 potently inhibits PU.1 binding IC50 of 10 nM and strongly inhibits the PU.1/DNA complex with high DB1976-?B affinity, KD of 12 nM in vitro. DB1976 has apoptosis-inducing effect.
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