GENERAL CATALOGUE
DB2313
HY-124629 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-124629
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Catalog No: HY-124629
CAS No: 2170606-74-1
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
DB2313 is a potent inhibitor of transcription factor PU.1. DB2313 inhibits PU.1-dependent reporter gene transactivation with an IC50 of 5 ?M. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis in acute myeloid leukemia AML cells and has anticancer effects.
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