GENERAL CATALOGUE
DBCO-PEG4-VC-PAB-MMAE
HY-136314 · 5 mg
MedChemExpress · Cat: HY-136314
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medchemexpress.com/dbco-peg4-vc-pab-mmae.htmlCatalog No: HY-136314
CAS No: 2129164-91-4
Category: Antibody-drug Conjugate ADC Related
Pack Size: 5 mg
Brand: MedChemExpress
Description
DBCO-PEG4-VC-PAB-MMAE consists a ADC linker DBCO-PEG4-VC-PAB and a tubulin polymerization inhibitor MMAE HY-15162 . DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates ADCs . MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition SPAAC with molecules containing Azide groups.
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