GENERAL CATALOGUE
dBET57
HY-123844 · 5 mg
MedChemExpress · Cat: HY-123844
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Catalog No: HY-123844
CAS No: 1883863-52-2
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
dBET57 is an effective and selective BRD4BD1 degrader based on PROTAC technology, with the ability to induce cell apoptosis and anti-tumor activity. dBET57 mediates the recruitment of the E3 ubiquitin ligase CRL4Cereblon, showing a DC50/5h value of 500 nM for BRD4BD1.
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