GENERAL CATALOGUE
DC0-NH2
HY-129379 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-129379
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medchemexpress.com/dc0-nh2.htmlCatalog No: HY-129379
CAS No: 615538-51-7
Category: Antibody-drug Conjugate ADC Related
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability. DC0-NH2 is about 1000-fold more cytotoxic than commonly used anticancer agents ex. Doxorubicin . DC0-NH2 can bind to the minor groove of DNA, followed by alkylation of adenine residues by its propabenzindole CBI component.