GENERAL CATALOGUE
DCG066
HY-116971 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-116971
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Catalog No: HY-116971
CAS No: 494786-13-9
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
DCG066 is an inhibitor of lysine methyltransferase G9a. DCG066 can bind directly to G9a and inhibit methyltransferase activity in vitro. DCG066 decreases di-methylation levels of histone H3 lysine 9 H3K9Me2 , inhibits cell proliferation and induces cell apoptosis. DCG066 displays low cytotoxicity in leukemia cell lines with high levels of G9a expression, including K562.
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