GENERAL CATALOGUE
DCLK1-IN-1
HY-135985 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-135985
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medchemexpress.com/dclk1-in-1.htmlCatalog No: HY-135985
CAS No: 2222635-15-4
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
DCLK1-IN-1 is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 DCLK1 kinase domain. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases IC50: DCLK1=9.5/57.2 nM and DCLK2=31/103 nM in binding and kinase assay, respectively . DCLK1-IN-1 shows low toxicity, and can investigate DCLK1 biology and establish its role in cancer, like DCLK1+ pancreatic ductal adenocarcinoma PDAC .
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