GENERAL CATALOGUE
DDO-2728
HY-155489 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-155489
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Catalog No: HY-155489
CAS No: 3029515-97-4
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
DDO-2728 compound 19 is a selective AlkB homologue 5 ALKBH5 inhibitor with an IC50 of 2.97 ?M. DDO-2728 increases the abundance of N6 methyladenosine m6A modifications, inducing cell apoptosis and cycle arrest. DDO-2728 suppresses tumor growth in the MV4 11 xenograft model with favorable safety profile, shows the potential of targeting ALKBH5 in cancer research.
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