GENERAL CATALOGUE
Deguelin
HY-13425 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13425
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medchemexpress.com/deguelin.html
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Catalog No: HY-13425
CAS No: 522-17-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-?B, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1?, COX-2, and NF-?B.
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