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Desmethylglycitein
GENERAL CATALOGUE

Desmethylglycitein

HY-N5072 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-N5072

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Catalog No: HY-N5072
CAS No: 17817-31-1
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Desmethylglycitein 4,6,7-Trihydroxyisoflavone , a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity. Desmethylglycitein is a direct inhibitor of protein kinase C PKC ?, against solar UV sUV -induced matrix matrix metalloproteinase 1 MMP1 . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes.

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