GENERAL CATALOGUE
Dexloxiglumide
HY-128878 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-128878
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medchemexpress.com/dexloxiglumide.htmlCatalog No: HY-128878
CAS No: 119817-90-2
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Dexloxiglumide is an orally active and selective cholecystokinin type A CCKA receptor antagonist. Dexloxiglumide is the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide CCK-8 . Dexloxiglumide exhibits moderate Caco-2 permeability that is polarized, concentration dependent, and pH dependent. Dexloxiglumide increases MRP1-substrate fluorescein uptake. Dexloxiglumide can be studied in research for gastrointestinal diseases and tumors.
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