GENERAL CATALOGUE
DFX117
HY-164384 · 50 mg
MedChemExpress · Cat: HY-164384
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medchemexpress.com/dfx117.html
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Catalog No: HY-164384
CAS No: 2125500-60-7
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
DFX117 is a selective, orally active inhibitor for PI3K? and c-Met tyrosine kinase. DFX117 inhibits PI3K/Akt/mTOR pathway, inhibits the proliferation of NCI-H1975, NCI-H1993, and HCC827 with IC50s 0.02-0.08 AAasAasAAmuM. DFX117 arrests cell cycle at G0/G1 phase, induces apoptosis in A549 and NCI-H1975. DFX117 exhibits antitumor efficacy in mice.
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