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DGAT-1 inhibitor 2
GENERAL CATALOGUE

DGAT-1 inhibitor 2

HY-50670 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-50670

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Catalog No: HY-50670
CAS No: 942999-61-3
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

DGAT-1 inhibitor 2 is an orally active DGAT-1 inhibitor with IC50 values of 15 nM and 9 nM for human DGAT-1 and rat DGAT-1, respectively. DGAT-1 inhibitor 2 increases ROS concentration, GRP78, and PERK protein abundance. DGAT-1 inhibitor 2 increases SREBF1, CPT1A, and MTTP mRNA in fatty acid-treated cells. DGAT-1 inhibitor 2 improves obesity.

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