GENERAL CATALOGUE
diABZI-i
HY-175167 · 50 mg
MedChemExpress · Cat: HY-175167
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medchemexpress.com/diabzi-i.html
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Catalog No: HY-175167
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
diABZI-i is a orthosteric STING inhibitor. diABZI-i significantly inhibits cGAMP-induced IFN? in PBMCs with an IC50 of 49 nM. diABZI-i also activates V155M SAVI constitutive signaling in STING V155M THP-1 cells model with potent agonism EC50:?17??nM . diABZI-i can be used for monogenic autoinflammatory disease like SAVI disease research.
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