GENERAL CATALOGUE
Diclofenac potassium
HY-15038 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-15038
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Catalog No: HY-15038
CAS No: 15307-81-0
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Diclofenac potassium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 ?M for ovine COX-1 and COX-2, respectively. Diclofenac potassium induces apoptosis of neural stem cells NSCs via the activation of the caspase cascade.
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