GENERAL CATALOGUE
Diflapolin
HY-128171 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-128171
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Catalog No: HY-128171
CAS No: 724453-98-9
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Diflapolin is a highly active dual 5-lipoxygenase-activating protein FLAP /soluble epoxide hydrolase sEH inhibitor with marked anti-inflammatory efficacy and high target selectivity. Diflapolin inhibits 5-LOX product formation in intact human monocytes and neutrophils with IC50s?of? 30 and 170?nM, respectively, and suppressed the activity of isolated sEH IC50=20?nM .
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