GENERAL CATALOGUE
Difluprednate
HY-17569 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-17569
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Catalog No: HY-17569
CAS No: 23674-86-4
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Difluprednate is a glucocorticoid receptor GC receptor agonist with a Ki of 0.78 nM. Difluprednates active metabolite 21-deacetylated difluprednate DFB is a competitive agonist of GC receptors with a Ki of 0.061 nM. Difluprednate binds to GC receptors through metabolism to DFB, regulating the transcription of inflammatory mediator genes, thereby exerting anti-inflammatory activity. Difluprednate can be used for research related to ocular inflammation, such as postoperative inflammation, anterior uveitis, etc.
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