GENERAL CATALOGUE
Disorazol A
HY-N14734 · 50 mg
MedChemExpress · Cat: HY-N14734
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Catalog No: HY-N14734
CAS No: 158181-47-6
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
Disorazol A1 is an tubulin inhibitor with antifungal activity. Disorazol A1 functions by inhibiting tubulin polymerization, interfering with microtubule formation, blocking mitosis, thus arresting the cell cycle at the G2/M phase and inducing apoptosis. Disorazol A1 also exhibits an inhibitory effect against L929 mouse fibroblasts with an IC50 value of 3 pM. Disorazol A1 causes the accumulation of p53 protein in the cell nucleus. Disorazol A1 is promising for research of cancers.
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