GENERAL CATALOGUE
Disulfiram
HY-B0240 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-B0240
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medchemexpress.com/disulfiram.htmlCatalog No: HY-B0240
CAS No: 97-77-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Disulfiram Tetraethylthiuram disulfide is a specific inhibitor of aldehyde-dehydrogenase ALDH1 , used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D GSDMD pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1? secretion in human and mouse cells. Disulfiram, a copper ion carrier,?with?Cu2+ increases intracellular ROS levels and induces cuproptosis.
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