GENERAL CATALOGUE
Divarasib adipate
HY-145928B · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-145928B
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Catalog No: HY-145928B
CAS No: 2762240-36-6
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Divarasib GDC-6036 adipate is an orally bioavailable, highly potent, and selective KRAS G12C inhibitor with an IC50 of 0.01 ?M. Divarasib covalently binds to the switch II SW-II pocket of KRAS G12C and irreversibly locks it in the inactive GDP-bound state.
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