DKK3 Mouse Monoclonal Antibody

Description

EnkiLife offers the DKK3 Mouse Monoclonal Antibody. This antibody reacts with Human,Monkey species and is suitable for WB,ELISA,FC application. Alternative Names of Immunogen: RIG; REIC. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Research Area: Wnt signaling pathway