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DM3-SMe
GENERAL CATALOGUE

DM3-SMe

HY-130081 · 50 mg

MedChemExpress · Cat: HY-130081

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medchemexpress.com/dm3-sme.html
Catalog No: HY-130081
CAS No: 796073-70-6
Category: Antibody-drug Conjugate ADC Related
Pack Size: 50 mg
Brand: MedChemExpress

Description

DM3-SMe is a maytansine derivative and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates ADCs , which can be linked to antibody through disulfide bond or stable thioether bond. DM3-SMe shows highly cytotoxic activity in vitro with an IC50 of 0.0011 nM.

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