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DM4-SPDP
GENERAL CATALOGUE

DM4-SPDP

HY-126493 · 50 mg

MedChemExpress · Cat: HY-126493

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medchemexpress.com/dm4-spdp.html
Catalog No: HY-126493
Category: Antibody-drug Conjugate ADC Related
Pack Size: 50 mg
Brand: MedChemExpress

Description

DM4-SPDP is a agent-linker conjugate composed of a potent antitubulin agent DM4 and a linker SMCC to make antibody agent conjugate. SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable reducible disulfide bonds with cysteine sulfhydryls.

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