GENERAL CATALOGUE
DNDI-8219
HY-124623 · 50 mg
MedChemExpress · Cat: HY-124623
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medchemexpress.com/dndi-8219.htmlCatalog No: HY-124623
CAS No: 2222660-40-2
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
DNDI-8219 compound 58 is a potent selective and orally active trypanocidal agent, possessing inhibitory activity against Trypanosoma cruzi T. cruzi with an IC50 of 0.4 ?M. DNDI-8219 has low cytotoxicity L6 cells IC50 100 ?M. DNDI-8219 can effectively cure chronic T. cruzi infection and markedly reduce parasite burdens in mouse model. DNDI-8219 has good solubility, metabolic stability and safety.