GENERAL CATALOGUE
DNMT1-IN-5
HY-172217 · 50 mg
MedChemExpress · Cat: HY-172217
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/dnmt1-in-5.htmlCatalog No: HY-172217
CAS No: 2982511-19-1
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
DNMT1-IN-5 Compound 55 is the inhibitor for DNMT that inhibits DNMT1 and DNMT3A with IC50 of 2.42 ?M and 14.4 ?M. DNMT1-IN-5 exhibits antiproliferative activity in a variety of cancer cell lines IC50s for TMD-8, DOHH2, MOLM-13, THP-1, RPIM-8226 and HCT116 are 0.19-2.37 ?M , arrests the cell cycle at G2/M phase, and induces apoptosis in TMD-8 and DOHH2 cells. DNMT1-IN-5 exhibits antitumor efficacy in TMD-8 xenograft mouse models.
More from MedChemExpress
2-Bromohexadecanoic acid
HY-111770
Apoptosis
Uridine 5'-monophosphate-15N2
HY-101981S
Apoptosis
AZD-5991
HY-101533
Apoptosis
HDAC-IN-37
HY-146750
Apoptosis
Anti-inflammatory agent 47
HY-155568
Apoptosis
YLT205
HY-117515
Apoptosis
pan-HER-IN-2
HY-144677
Apoptosis
HDAC-IN-84
HY-170379
Apoptosis