GENERAL CATALOGUE
Dolutegravir sodium
HY-13238A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-13238A
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medchemexpress.com/Dolutegravir-sodium.htmlCatalog No: HY-13238A
CAS No: 1051375-19-9
Category: Anti-infection
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Dolutegravir sodium S/GSK1349572 sodium is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir sodium S/GSK1349572 sodium inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir sodium S/GSK1349572 sodium retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants EC50=3.6-5.8 nM .
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