GENERAL CATALOGUE
Dopamine D4 receptor ligand 3
HY-173431 · 50 mg
MedChemExpress · Cat: HY-173431
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Manufacturer product page
medchemexpress.com/dopamine-d4-receptor-ligand-3.htmlCatalog No: HY-173431
CAS No: 3082344-46-2
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
Dopamine D4 receptor ligand 3 Compound 16 is a dopamine D4 receptor D4R antagonist pKi: 8.86 . Dopamine D4 receptor ligand 3 has pIC50 values of 5.78, 5.55, and 6.17 for Go, Gi, and ?Arr2 sensors in HEK-293T cells, respectively. Dopamine D4 receptor ligand 3 inhibits the viability of three human glioma cell lines, U87 MG, T98G, and U251 MG. Dopamine D4 receptor ligand 3 induces ROS production and mitochondrial dysfunction in glioma cells.
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