Doramapimod (Standard)

Description

Doramapimod Standard is the analytical standard of Doramapimod. This product is intended for research and analytical applications. Doramapimod BIRB 796 is an orally active, highly potent p38 MAPK inhibitor, which has an IC50 for p38?=38 nM, for p38?=65 nM, for p38?=200 nM, and for p38?=520 nM. Doramapimod has picomolar affinity for p38 kinase Kd=0.1 nM . Doramapimod also inhibits B-Raf with an IC50 of 83 nM.