

HY-101520 · 50 mg
MedChemExpress · Cat: HY-101520
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medchemexpress.com/Dot1L-IN-1.htmlDescription
Dot1L-IN-1 is a highly potent and selective Dot1L inhibitor with a Ki of 2 pM and an IC50 of 0.1 nM. Dot1L-IN-1 potently suppresses H3K79 dimethylation IC50=3 nM , as well as the activity of the HoxA9 promoter IC50=17 nM in HeLa and Molm-13 cells, respectively.

